WD138 2022：Biological and pharmacological roles of pyroptosis in pulmonary

wd138 2022   wd138 real In 2022, Deng and colleagues discovered that GSDMA undergoes specific cleavage by the group A streptococcus cysteine protease SpeB at Gln246, which triggers keratinocyte pyroptosis and enhances skin antimicrobial defence . However, further research is warranted to ascertain the potential of other proteases for activating GSDMA

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