JUVENILE DIABETES：Dysglycaemia definitions and progression to clinical type 1

juvenile diabetes   zeus138 The presymptomatic phase of type 1 diabetes is marked by the presence of two or more islet autoantibodies, classified into normoglycaemia stage 1 and dysglycaemia stage 2.1–3 These stages guide the indication of therapies such as the anti-CD3 antibody, teplizumab, which is FDA approved for children aged 8 years or older with stage 2 type 1 diabetes. In the past decade, criteria for stage

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