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rtp e200m The optimized RTP-BLSs showed a significantly higher brain drug targeting efficiency 279.16 ± 6.37% as compared to RTP-Sol 126.15 ± 4.79% given intranasally. From our findings, it can be concluded that the developed BLSs are novel alternative RTP carriers for direct nose-to-brain delivery for the improvement of brain drug targeting

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